Donor Age, Cold Ischemia Time, and Delayed Graft Function
نویسندگان
چکیده
منابع مشابه
Xenon Treatment Protects Against Cold Ischemia Associated Delayed Graft Function and Prolongs Graft Survival in Rats
Prolonged hypothermic storage causes ischemia-reperfusion injury (IRI) in the renal graft, which is considered to contribute to the occurrence of the delayed graft function (DGF) and chronic graft failure. Strategies are required to protect the graft and to prolong renal graft survival. We demonstrated that xenon exposure to human proximal tubular cells (HK-2) led to activation of range of prot...
متن کاملMajor effects of delayed graft function and cold ischaemia time on renal allograft survival.
BACKGROUND There is mounting evidence from experimental and clinical studies that the quality of organs from cadaver donors may be influenced by events occurring around the time of brain death, and that these may affect transplant outcome. The aim of this study is to investigate the influence of donor factors on renal allograft outcome in a homogeneous cohort of 518 patients transplanted in a s...
متن کاملDonor Diabetes and Prolonged Cold Ischemia Time Synergistically Increase the Risk of Graft Failure After Liver Transplantation
BACKGROUND Both prolonged cold ischemia time (CIT) and donor history of diabetes mellitus (DM) are associated with reduced graft survival after liver transplantation. However, it is unknown whether the adverse effect of prolonged CIT on posttransplant graft survival is more pronounced after transplant with DM versus non-DM donor grafts. METHODS The study sample included 58 226 liver transplan...
متن کاملDelayed Graft Function
Delayed graft function (DGF) is a common complication of renal transplantation. According to a clinical data analysis of 34,647 cases of cadaveric renal transplantation documented by the Renal Transplantation Registry of the United Network Sharing (UNOS), graft function did not recover instantly after transplantation and for ever in some cases; the 1-year rate of graft loss was up to 20% in cas...
متن کاملEffect of donor-recipient age difference on graft function and survival in live-donor kidney transplantation.
BACKGROUND Renal transplant recipients of older deceased-donor kidneys have reduced allograft survival. However, the impact of donor-recipient age difference on live-donor kidney transplant outcomes, where donors are older than recipients, remains unclear. METHODS Using the Australia and New Zealand Dialysis and Transplant Registry, all primary live-donor kidney transplant recipients in Austr...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2020
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.13711119